A review of Mechanism of Schiff bases formation Potential problem in Schiff base formation
Keywords:
Schiff base formation, Schiff base, aldehyde, compound, carbinolamineAbstract
The general consensus of the mechanism of Schiff base formation, as shown in Figure, is nucleophilic addition to the carbonyl group. In the Schiff base formation, the nucleophile is the primary amine. In the first part of the mechanism, the lone pair of electrons in the amine nitrogen attacks the aldehyde or ketone to give an unstable addition compound called a carbinolamine.
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