Review of various application of metal complexes of schiff bases as an antimicrobial drug

Authors

  • Priyanka Devi Ahir College Rewari

Keywords:

Schiff bases, Metal complexes, Microorganism, antimicrobial

Abstract

Schiff bases are versatile ligands which are synthesized from the condensation of primary amines with carbonyl groups. Synthesis of Schiff base transition metal complexes by using Schiff base as ligands appears to be fascinating in view of the possibility of obtaining coordination compounds of unusual structure and stability. These transition metal complexes have received exceptional consideration because of their active part in metalloenzymes and as biomimetic model compounds due to their closeness to natural proteins and enzymes. These compounds are very important in pharmaceutical fields because of their wide spectrum of biological activities. Most of them show biological activities including antibacterial, antifungal, antidiabetic, antitumor, antiproliferative, anticancer, herbicidal, and anti-inflammatory activities. The biological activity of the transition metal complexes derived from the Schiff base ligands has been widely studied. This review summarizes the importance, Scope and antimicrobial activities of Schiff base metal complexes.

References

Shamsipur M, Ghiasvand AR. Solid phase extraction of ultra trace copper(II) using octadecyl silica membrane disks modified by a naphthol derivative schiff’s base. Anal Chim Acta 2000;408:271-7.

Reddy KK, Sayaji R, Biyyala SR. Synthesis and characterization and biological activities of hydrazones. Int J Innovative Res Sci Eng Technol 2015;4:18944-52

Qiu M, Liu G, Yao X, Guo M, Pan G, Zheng ZC. Copper(II)-schiff base complexes as catalysts for asymmetric cyclopropanation of styrene. Chin J Catal 2001;22:77-80.

Zhuo-Hong Yang, Li-Xin Wang, Zheng-Hong Zhou, Qi-Lin Zhou, Chu-Chi Tang. Synthesis of new chiral schiff bases and their application in the asymmetric trimethylsilyl cyanation of aromatic aldehydes. Tetrahedron Asymmetry 2001;12:1579-82.

Jose ES, Edward RS, Cavalheirob ETG. Synthesis and characterization of schiff bases from chitosan and salicylaldehyde derivatives. Carbohydrates Polymer 2005;60:277-82.

Alexander V. Design and synthesis of macrocyclic ligands and their complexes of lanthanides and actinides. Chem Rev 1995;95:273-342.

Quiruga AG, Ranninger CN. Review contribution to the SAR field of metallated and coordination complexes: studies of the palladium and platinum derivatives with selected thiosemicarbazones as antitumoral drugs. Coord Chem Rev 2004;248:119-33.

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Published

31-12-2015

How to Cite

Priyanka Devi. (2015). Review of various application of metal complexes of schiff bases as an antimicrobial drug. International Journal for Research Publication and Seminar, 6(7). Retrieved from https://jrps.shodhsagar.com/index.php/j/article/view/692

Issue

Vol. 6 No. 7 (2015): Volume 6 | Issue 7 | Oct-Dec 2015

Section

Original Research Article

License

Copyright (c) 2015 International Journal for Research Publication and Seminar

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