The effect of coronavirus disease 2019 on newborns

Authors

  • Dr Anil Kumar Gupta Assistant Professor, Department of Paediatrics World College Of Medical Sciences and Research Jhajjar, Haryana

Keywords:

coronavirus disease 2019, development, newborn, pregnancy

Abstract

To evaluate the available literature regarding effects of coronavirus disease 2019 (COVID-19) on newborns, ranging from effects related to in utero and perinatal exposure to maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, to pandemic-related stress and socioeconomic changes.
Recent findings
Risk of vertical transmission from SARS-CoV-2 infected women to their babies seems to be low and unrelated to postnatal care practises such mother-newborn separation and breastfeeding, according to many major studies and national registries. Premature birth is an additional risk factor for infants exposed to SARS-CoV-2 in the womb. In most cases, SARS-CoV-2 infection in infants has a mild clinical presentation. Although there is a paucity of long-term follow-up data, early studies suggest that, like other natural catastrophes, being born during the pandemic may be linked to developmental risk.
Summary
Early evidence show developmental danger to the generation born during the pandemic, notwithstanding the minimal probability of vertical or perinatal transmission across a variety of postnatal care methods. The long-term effects of SARS-CoV-2 and the COVID-19 pandemic exposure during pregnancy and early childhood are not well understood.

References

Zimmermann P, Curtis N. Coronavirus infections in children including COVID-19. Pediatr Infect Dis J. (2020) 39:355–68. doi: 10.1097/INF.0000000000002660

Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. (2020). 145:e20200702. doi: 10.1542/peds.2020-0702

Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. (2020). 181: 271.e8–80.e8. doi: 10.1016/j.cell.2020.02.052

Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 infection in children. N Engl J Med. (2020) 382:1663–5. doi: 10.1056/NEJMc2005073

Panetta L, Proulx C, Drouin O, Autmizguine J, Luu TM, Quach C, et al. Clinical characteristics and disease severity among infants with SARS-CoV-2 infection in Montreal, Quebec, Canada. JAMA Netw Open. (2020). 3:e2030470. doi: 10.1001/jamanetworkopen.2020.30470

Gale C, Quigley MA, Placzek A, Knight M, Ladhani S, Draper ES, et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child Adolesc Health. (2021) 5:113–21. doi: 10.1016/S2352-4642(20)30342-4

Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang Z-J. Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA. (2020) 323:1313–4. doi: 10.1001/jama.2020.2131

Alharbi M, Kazzaz YM, Hameed T, Alqanatish J, Alkhalaf H, Alsadoon A, et al. SARS-CoV-2 infection in children, clinical characteristics, diagnostic findings and therapeutic interventions at a tertiary care center in Riyadh, Saudi Arabia. J Infect Public Health. (2021) 14:446–53. doi: 10.1016/j.jiph.2020.12.034

Nezar Kobeisy SA, Harbi SA, Mehdawi RS, Bashammakh DS. Pediatric COVID-19 patients in Jeddah, Saudi Arabia: clinical, laboratory and radiological aspects. J Biomed Sci. (2020).9. doi: 10.36648/2254-609x.9.3.7

Multisystem Inflammatory Syndrome in Children and Adolescents with COVID-19. WHO (2020). Available from: https://www.who.int/docs/default-source/coronaviruse/sb-2020-1-multisystem-syndrome-2020-05-15-e.pdf?sfvrsn=6fe7a115_2 (accessed May 16, 2021).

De Rose, D. U., Piersigilli, F., Ronchetti, M. P., Santisi, A., Bersani, I., Dotta, A., Danhaive, O., & Auriti, C. (2020). Novel Coronavirus disease (COVID-19) in newborns and infants: What we know so far. Italian Journal of Pediatrics, 46(1), 4–11. https://doi.org/10.1186/s13052-020-0820-x

Indian Council of Medical Research. (2020). Guidance for Management of Pregnant Women in COVID-19 Pandemic. National Institute for Research in Reproductive Health, 1–17.

Kyle, M. H., & Dumitriu, D. (2021). The effect of coronavirus disease 2019 on newborns. Current Opinion in Pediatrics, 33(6), 618–624. https://doi.org/10.1097/MOP.0000000000001063

Priya, P. G., Daya, P. A., Anithasri, A., & Karthikeyan, G. (2022). Impact of Corona Virus Disease in Pregnancy and Newborn. Journal of Communicable Diseases, 2022(109), 109–114. https://doi.org/10.24321/0019.5138.202217

Singhal, T. (2020). A Review of Coronavirus Disease-2019 (COVID-19). Indian Journal of Pediatrics, 87(4), 281–286. https://doi.org/10.1007/s12098-020-03263-6

Yıldız, G., Kurt, D., Mat, E., Yıldız, P., Başol, G., Gündogdu, E. C., Kuru, B., Topcu, B., & Kale, A. (2022). Hearing test results of newborns born from the coronavirus disease 2019 (COVID-19) infected mothers: A tertiary center experience in Turkey. Journal of Obstetrics and Gynaecology Research, 48(1), 113–118. https://doi.org/10.1111/jog.15008

Yu, Y., & Chen, P. (2020). Coronavirus Disease 2019 (COVID-19) in Neonates and Children From China: A Review. Frontiers in Pediatrics, 8(May), 1–12. https://doi.org/10.3389/fped.2020.00287

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Published

31-12-2022

How to Cite

Dr Anil Kumar Gupta. (2022). The effect of coronavirus disease 2019 on newborns. International Journal for Research Publication and Seminar, 13(5), 122–131. Retrieved from https://jrps.shodhsagar.com/index.php/j/article/view/254

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Section

Original Research Article