Adverse Drug Reactions: Mechanisms, Detection, and Prevention Strategies
DOI:
https://doi.org/10.36676/jrps.v14.i1.1613Keywords:
Adverse drug reactions, ADR mechanisms, PharmacokineticsAbstract
Adverse drug reactions, often known as ADRs, are a significant concern in clinical medicine that can have an effect on both the safety of patients and the outcomes of their healthcare. the processes, methods of detection, and preventative measures that are associated with adverse drug reactions (ADRs). Among the most important subjects are the various molecular mechanisms that are responsible for adverse drug reactions (ADRs). These mechanisms include pharmacokinetic aspects including metabolism and excretion, as well as pharmacodynamic interactions at the cellular and molecular levels. In the realm of detection approaches, pharmacovigilance systems, electronic health records (EHRs), and data mining techniques are included. These technologies allow for the timely identification and monitoring of adverse drug reactions (ADRs) across a wide range of patient populations. Pharmacogenomics, personalised medicine techniques, and breakthroughs in drug safety testing are the primary focusses of prevention tactics. These strategies aim to reduce the likelihood of adverse responses occurring prior to the utilisation of the drug in clinical settings.
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