Extraction, Characterization, and Biological Activities of Phytochemicals from Terminalia Arjuna (Arjuna) Plant

Atul Kumar Singh; Arun Kumar

doi:10.36676/jrps.v15.i2.1410

Authors

Atul Kumar Singh Research scholar, Department of Chemistry, Hindu Post Graduate, Zamania, Ghazipur U.P - 232331, India
Arun Kumar Professor, Department of Chemistry Hindu Post Graduate College, Zamania, Ghazipur U.P -232331, India

DOI:

https://doi.org/10.36676/jrps.v15.i2.1410

Keywords:

Arjuna, Phytochemicals, Medicinal properties, Characterization, Applications

Abstract

This study focuses on the comprehensive characterization and biological activities of phytochemicals from the bark of Terminalia Arjuna (Arjuna). The bark, known for its medicinal properties, was extracted using methanol and analyzed for its phytochemical profile. The study employed various spectroscopic methods including Fourier transform infrared (FTIR), 1H NMR and 13C NMR spectroscopy. The antioxidant and anti-inflammatory activities were also evaluated while antimicrobial activity was assessed against both Gram-positive and Gram-negative bacteria. Additionally, the study included characterization by nuclear magnetic resonance (NMR) spectroscopy (1H and 13C) and infrared (IR) spectroscopy, as well as the determination of acid value, peroxide value, and the presence of aflatoxins. The results provide valuable insights into the potential therapeutic applications of Terminalia arjuna and its phytochemical constituents.

References

Li P-H, Wang C-W, Lu W-C, Song T-Y, Wang C-CR. Antioxidant, Anti-Inflammatory Activities, and Neuroprotective Behaviors of Phyllanthus emblica L. Fruit Extracts. Agriculture. 2022; 12(5):588. https://doi.org/10.3390/agriculture12050588 DOI: https://doi.org/10.3390/agriculture12050588

Verma, V. and Jogdand, S. (2021) “Medicinal Properties of Terminalia Arjuna: A Review”, Journal of Pharmaceutical Research International, 33(62A), pp. 593–604. doi: 10.9734/jpri/2021/v33i62A35893. DOI: https://doi.org/10.9734/jpri/2021/v33i62A35893

Abo-Elghiet, F., Abd-elsttara, A., Metwaly, A., & Mohammad, A. (2022). Antioxidant, anti-inflammatory, and antimicrobial evaluation of Terminalia arjuna leaves, fruits, and bark. Azhar International Journal of Pharmaceutical and Medical Sciences, 2(2), 148-158. doi: 10.21608/aijpms.2022.127469.1117 DOI: https://doi.org/10.21608/aijpms.2022.127469.1117

Vikas Kumar, Nitin Sharma, Rakshandha Saini, Smita Mall, Gokhan Zengin, Anuradha Sourirajan, Prem Kumar Khosla, Kamal Dev, Mohamed El-Shazly, Therapeutic potential and industrial applications of Terminalia arjuna bark, Journal of Ethnopharmacology, Volume 310, 2023, 116352, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2023.116352. DOI: https://doi.org/10.1016/j.jep.2023.116352

Tahsin MR, Sultana A, Mohtasim Khan MS, Jahan I, Mim SR, Tithi TI, Ananta MF, Afrin S, Ali M, Hussain MS, Chowdhury JA, Kabir S, Chowdhury AA, Amran MS, Aktar F. An evaluation of pharmacological healing potentialities of Terminalia Arjuna against several ailments on experimental rat models with an in-silico approach. Heliyon. 2021 Oct 20;7(11):e08225. doi: 10.1016/j.heliyon.2021.e08225. PMID: 34816025; PMCID: PMC8591345. DOI: https://doi.org/10.1016/j.heliyon.2021.e08225

R V, N A, S R, Mahendra J. Antimicrobial and anti-inflammatory activity of Terminalia arjuna. Bioinformation. 2023 Feb 28;19(2):184-189. doi: 10.6026/97320630019184. PMID: 37814683; PMCID: PMC10560303. DOI: https://doi.org/10.6026/97320630019184

Vikas Kumar, Nitin Sharma, Anuradha Sourirajan, Prem Kumar Khosla, Kamal Dev, Comparative evaluation of antimicrobial and antioxidant potential of ethanolic extract and its fractions of bark and leaves of Terminalia arjuna from north-western Himalayas, India, Journal of Traditional and Complementary Medicine, Volume 8, Issue 1, 2018, Pages 100-106, ISSN 2225-4110, https://doi.org/10.1016/j.jtcme.2017.04.002. DOI: https://doi.org/10.1016/j.jtcme.2017.04.002

Singh PK, Singh J, Medhi T, Kumar A. Phytochemical Screening, Quantification, FT-IR Analysis, and In Silico Characterization of Potential Bio-active Compounds Identified in HR-LC/MS Analysis of the Polyherbal Formulation from Northeast India. ACS Omega. 2022 Sep 7;7(37):33067-33078. doi: 10.1021/acsomega.2c03117. PMID: 36157760; PMCID: PMC9494667. DOI: https://doi.org/10.1021/acsomega.2c03117

Skoog, D.A., Holler, F.J., & Crouch, S.R. (2007). Principles of Instrumental Analysis (6th ed.). Thomson Brooks/Cole.

P.S. Kalsi, Spectroscopy of Organic Compounds 5th Edition, 2002.