Nanotoxicology: A Threat to the Environment and to Mankind

Authors

  • Dr. Vishal Pathak Assistant Professor Deptt. Of Chemistry, Paliwal (P.G.) College Shikohabad. (U.P.)

Keywords:

Nanomaterials, characterization techniques, nanotoxicology

Abstract

Nanotoxicology represents a new and growing research area in toxicology. It deals with the assessment of the toxicological properties of nanoparticles (NPs) with the intention of determining whether (and to what extent)they pose an environmental or societal threat. Inherent properties of NPs (including size, shape, surface area, surface charge, crystal structure, coating, and solubility/dissolution) as well as environmental factors (such as temperature, pH, ionic strength, salinity, and organic matter) collectively influence NP behavior, fate and transport, and ultimately toxicity. The nanotoxicology researchers focused on the relationship between nanomaterial characteristics (size, shape, surface area etc.) and toxic responses (cytotoxicity, genotoxicity, inflammation etc.). This article aims to give a brief summary of what is known today about nanotoxicology.

References

Arora S, Rajwade JM, Paknikar KM, Nanotoxicology and in vitro studies: The need of the hour, Toxicol Appl Pharm 258(2), 151- 165, 2012.

Singh N, Manshian B, Jenkins GJS, Griffiths SM, Williams PM, Maffeis TGG, Wright CJ, Doak SH, NanoGenotoxicology:The DNA damaging potential of engineered nanomaterials, Biomaterials 30(23-24), 3891-3914, 2009.

Donaldson K, Stone V, Tran CL, Kreyling W, Borm PJA, Nanotoxicology, Occup Environ Med 61(9), 727-728, 2004.

Dockery DW, Pope CA, Xu X, Spengler JD, Ware JH, Fay ME, Ferris Jr BG, Speizer FE, An association between air pollution and mortality in six US cities, N Engl J Med 329(24), 1753-1759, 1993.

Kane AB, Hurt RH, Nanotoxicology: the asbestos analogy revisited, Nat Nanotech 3(7), 378-379, 2008.

Elsaesser A, Howard CV, Toxicology of nanoparticles, Adv Drug Delivery Rev 64(2), 129-137, 2012.

Vance ME, Kuiken T, Vejerano EP, McGinnis SP, Hochelle Jr MF, Rejeski D, Hull MS.Nanotechnology in the real world: redeveloping the nanomaterials consumer products inventory. Journal of Nanotechnology.;6:1769–1780. doi:10.3762/bjnano.6.181. 2015.

Toensmeier PA. Nanotechnology faces scrutiny over environment and toxicity. Plastics Engineering.;60(11):14–17. 2004.

Oberdorster E, Zhu SQ, Blickley TM, Clellan-Green P, Haasch ML. Ecotoxicology of carbon-based engineered nanoparticles: effects of fullerene (C-60) on aquatic organisms.Carbon.;44(6):1112–1120. doi:10.1016/j.carbon.2005.11.008. 2006.

Moore MN. Do nanoparticles present ecotoxicological risks for the health of the aquatic environment? Environment International. 2006;32(8):967–976. doi:10.1016/j.envint..06.014. 2006.

Klaine SJ, Alvarez PJJ, Batley GE, Gernandes TF, Handy RD, Lyon DY, Mahendra S,McLaughlin MJ, Lead JR. Nanomaterials in the environment: behaviour, fate, bioavailability,and effects. Environmental Toxicology and Chemistry.;27(9):1825–1851.doi:10.1897/08-090.1. 2008.

Downloads

Published

30-09-2020

How to Cite

Dr. Vishal Pathak. (2020). Nanotoxicology: A Threat to the Environment and to Mankind. International Journal for Research Publication and Seminar, 11(3), 140–147. Retrieved from https://jrps.shodhsagar.com/index.php/j/article/view/1174

Issue

Section

Original Research Article